KMID : 1141320180330010085
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Kosin Medical Journal 2018 Volume.33 No. 1 p.85 ~ p.90
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IgA nephropathy in a patient with ankylosing spondylitis well controlled with etanercept
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Lee Do-Hyeong
Kim Geun-Tae Hwang Na-Kyoung Kim Eun-Heui
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Abstract
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Ankylosing spondylitis (AS) can involve the eye, gastrointestinal system, cardiopulmonary system, skin, kidneys, and spinal and peripheral joints. It is rarely accompanied by immunoglobulin A (IgA) nephropathy. Although IgA is involved in both AS and IgA nephropathy, the relationship between these diseases remains unclear. We detected hematuria and proteinuria in a 32-year-old male patient with ankylosing spondylitis that remained stable for 4 years through treatment with etanercept, a tumor necrosis factor-¥á (TNF-¥á) inhibitor, and diagnosed IgA nephropathy through a renal biopsy. IgA nephropathy seems to be less commonly associated with AS disease activity or specific treatment such as TNF-¥á inhibitor use.
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KEYWORD
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Ankylosing spondylitis, IgA glomerulonephritis, Tumor necrosis factor alpha
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